← All biomarkers
Lipidomics · Unsaturated Acylcarnitine — Salivary Analysis

2-trans-octenoylcarnitine

2-trans-Octenoylcarnitine is an unsaturated medium-chain acylcarnitine intermediate of mitochondrial fatty-acid β-oxidation, accumulating as acyl-CoA species are buffered through the carnitine shuttle during fat oxidation. Its salivary abundance tracks the mobilisation of mitochondrial lipid oxidation under exercise energy demand. Wenzel et al. (2026) identified it among the salivary acylcarnitines that reliably distinguish recent exercise, and Lehmann et al. (2010) showed medium-chain acylcarnitines dominate the exercise metabolite signature.

References

  1. Targeted saliva multi-omics is a reliable, non-invasive method to capture physiological stress and recoveryWenzel C, Kalaycik B, … Zimmer P. · TU Dortmund University · 2026
  2. Medium chain acylcarnitines dominate the metabolite pattern in humans under moderate intensity exercise and support lipid oxidationLehmann R et al. · PLoS One · 2010 — PubMed