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Metabolomics · Hydration Marker — Salivary Analysis

Protein Concentration

Total salivary protein concentration reflects the composite output of all proteins secreted into the oral cavity and rises inversely with salivary flow rate as dehydration progresses. Walsh et al. (2004) demonstrated strong correlation between salivary protein concentration and exercise-induced dehydration, validating it as a sensitive non-invasive fluid-balance marker. It complements creatinine as a dual-marker hydration assessment in athletic populations.

References

  1. Is this elderly patient dehydrated? Diagnostic accuracy of hydration assessment using physical signs, urine, and saliva markersFortes MB et al. · J Am Med Dir Assoc · 2015 — PubMed
  2. Saliva flow rate, total protein concentration and osmolality as potential markers of whole body hydration status during progressive acute dehydration in humansWalsh NP et al. · Arch Oral Biol · 2004 — PubMed